As we mentioned in previous articles, infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse or can not carry the pregnancy to term. It effects over 5 millions couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist. the unexplained causes of infertility is defined as if the woman and men reproductive system are function normally but the present-day medical technology and medical doctors can not give a reason why the couple can not conceive .In this article, we will discuss what is male infertility hemizona assay?
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I. Definition
Hemizona assay is an analysis to compare the binding capacity of sample sperm of the unfertilized male to the sperm of the fertilized male through manual hand cutting versus micro manipulation in IVF and IUI fertilization.
II. Diagnosis
After splitting the mature and normal egg in half. 1/2 is tested by sample sperm of the infertile male and the other half is tested by the fertilized male sperm through manual hand cutting or micro manipulation. Then the number of sperm bounds to each half and is calculated, and the infertile male's sperm is divided by that from the fertile male's sperm. A figure of less than 0.60 indicates abnormal infertile male's sperm.
Although the success rate of this test is not 100%, the HZA has been found to be predictive of IVF and IUI outcome with positive and negative values of 83% and 95% respectively, according to one study. Therefore, if an infertile couple decides to go through IUI or IVF for conception then the hemizoma test is necessary.
III. Risk
There is no guarantee that a couple who scores high in the hemizoma test will be successful to conceive via IVF or IUI, because there are other factors that may interfere with the process after the fertilized egg or embryo was implanted into the uterus.
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I hope this information will help you understanding more of the causes of infertility in women and men, if you need more information, please visit
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